Brian Roche: Survival has Consequences
Knowing ‘now’ what we should have know ‘then’ is the basis of Brian Roche’s research. He will reveal to you the unsettling truth about the development of chemotherapy drugs and how, as cancer survivors who have taken them, face an uncertain cardiovascular future. And as his unexpected side effect, he may help redefine the methodology for all human trials in pharmaceuticals.
ABOUT TEDx
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ABOUT Brian Roche
“Brian Roche, Ph.D. in Cardiovascular Physiology is Battelle Memorial Institute’s Manager of Safety Pharmacology.
He is a principal research scientist with 12 years experience in the field of cardiovascular safety pharmacology. He has directed a variety of in vivo studies, both GLP and non-GLP, primarily with cardiovascular, respiratory and CNS parameters as the study end-points.
He is also the technical lead for development of predictive and translatable model systems to investigate drug-induced cardiac injury and late discovery studies along with development of new innovative assays.
Dr Roche is a Board certified toxicologist focusing on toxicological and pharmacological evaluations of compounds for Investigational New Drug (IND) and New Drug Applications (NDA) to the Food and Drug Administration (FDA) and other regulatory bodies for thorough QT studies (E14), phase 0, 1-3 clinical studies, and to select appropriate first-in-human (FIH) doses.”
The VIDEO
